Effect of crush and axotomy of phrenic nerves on oxidative stress in diaphragm muscle of rats
 
Yazarlar (6)
Prof. Dr. Fuat Sayır Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Servet KAVAK Muğla Sıtkı Koçman Üniversitesi, Türkiye
İsmail Meral
Bezm-İ Âlem Vakıf Üniversitesi, Türkiye
Prof. Dr. Halit Demir Yüzüncü Yıl Üniversitesi, Türkiye
Nurettin Cengiz
Van Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Ufuk Çobanoğlu Yüzüncü Yıl Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Muscle and Nerve (Q2)
Dergi ISSN 0148-639X Dergi Bilgileri (2012)
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 03-2012
Cilt / Sayı / Sayfa 45 / 3 / 412–415 DOI 10.1002/mus.22312
Makale Linki http://doi.wiley.com/10.1002/mus.22312
UAK Araştırma Alanları
Biyofizik
Özet
Introduction: In this study we investigated the effect of crush and axotomy of phrenic nerves on oxidative stress and antioxidant enzyme activities in rat diaphragm muscle. Methods: The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Results: The malondialdehyde level increased in diaphragm muscles after both crush and axotomy. The antioxidant enzymes, such as superoxide dismutase, glutathione peroxidase, carbonic anhydrase, and catalase, decreased in diaphragm muscles after both crush and axotomy. Conclusions: Crushing or axotomizing the phrenic nerves may produce oxidative stress in the diaphragm muscle of the rat by increasing lipid peroxidation and decreasing antioxidant enzyme activities. Muscle Nerve, 2012
Anahtar Kelimeler
Antioxidant enzyme | Diaphragm muscle | Oxidative stress | Phrenic nerve degeneration | Rat
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 5
Scopus 4
Google Scholar 7
Effect of crush and axotomy of phrenic nerves on oxidative stress in diaphragm muscle of rats

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