The Effects of Phrenic Nerve Degeneration by Axotomy and Crush on the Electrical Activities of Diaphragm Muscles of Rats
Yazarlar (4)
Doç. Dr. Mehmet Eşref Alkiş Muş Alparslan Üniversitesi, Türkiye
Prof. Dr. Servet KAVAK Muğla Sıtkı Koçman Üniversitesi, Türkiye
Fuat Sayır Van Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Aydin Him Ondokuz Mayis Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Cell Biochemistry and Biophysics (Q4)
Dergi ISSN 1085-9195 Dergi Bilgileri (2016)
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 03-2016
Cilt / Sayı / Sayfa 74 / 1 / 29–34 DOI 10.1007/s12013-015-0708-3
Makale Linki http://link.springer.com/10.1007/s12013-015-0708-3
UAK Araştırma Alanları
Biyofizik
Özet
The aim of this study was to investigate the effect of axotomy and crush-related degeneration on the electrical activities of diaphragm muscle strips of experimental rats. In the present study, twenty-one male Wistar-albino rats were used and divided into three groups. The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Resting membrane potential (RMP) was decreased significantly in both crush and axotomy of diaphragm muscle strips of experimental rats (p < 0.05). Depolarization time (TDEP) and half-repolarization (1/2 RT) time were significantly prolonged in crush and axotomy rats (p < 0.05). Crushing or axotomizing the phrenic nerves may produce electrical activities in the diaphragm muscle of the rat by depolarization time and half-repolarization time prolonged in …
Anahtar Kelimeler
Diaphragm muscle | Electro-biophysics | Phrenic nerves | Rats