The Prolidase Activity, Oxidative Stress, and Nitric Oxide Levels of Bladder Tissues with or Without Tumor in Patients with Bladder Cancer
 
Yazarlar (8)
İlhan Geçit İnönü Üniversitesi, Türkiye
Recep Eryılmaz Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Servet KAVAK Muğla Sıtkı Koçman Üniversitesi, Türkiye
İsmail Meral Bezm-İ Âlem Vakıf Üniversitesi, Türkiye
Prof. Dr. Halit Demir Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Necip Pirinççi Fırat Üniversitesi, Türkiye
Arş. Gör. Mustafa Güneş Sağlık Bilimleri Üniversitesi, Türkiye
Prof. Dr. Kerem Taken Yüzüncü Yıl Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Membrane Biology (Q3)
Dergi ISSN 0022-2631 Dergi Bilgileri (2017)
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 08-2017
Cilt / Sayı / Sayfa 250 / 5 / 455–459 DOI 10.1007/s00232-017-9971-0
Makale Linki http://link.springer.com/10.1007/s00232-017-9971-0
UAK Araştırma Alanları
Biyofizik
Özet
This study was designed to evaluate the malondialdehyde (MDA), glutathione (GSH) and nitric oxide (NO) levels, and also prolidase, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) enzyme activities in malignant and benign cancers of bladder tissue. A total of 59 patients admitted to our clinic due to microscopic or macroscopic haematuria, were prospectively included in the study. Because of some reasons (no request to participate in the study, the inability to reach, other malignancies, alcohol consumption, metabolic disease), eight patients were excluded from study. Of the 51 patients, 25 were bladder tumor patients, and 26 were patients without cancers. The bladder tissue samples were obtained from all patients under anesthesia (spinal, epidural or general) for the measurement of MDA, GSH and NO levels, and prolidase, GSH-Px and SOD enzyme activities. Among the patients with bladder …
Anahtar Kelimeler
Bladder | Cancer | Nitric oxide | Oxidative stress | Status antioxidants | Superoxide dismutase