Levels of oxidative stress, selenium and zinc, and health-related quality of life in healthy males before and after COVID-19 vaccination
Yazarlar (9)
Doç. Dr. Kadirhan ÖZDEMİR İzmir Bakırçay Üniversitesi, Türkiye
Ercan Saruhan Muğla Sıtkı Koçman Üniversitesi, Türkiye
Öğr. Gör. Tuba Kaya Benli İzmir Bakırçay Üniversitesi, Türkiye
Arş. Gör. Gözde KAYA UÇAR İzmir Bakırçay Üniversitesi, Türkiye
Melike Yüksel
Türkiye
Melike Yüksel Yavuz İzmir Katip Çelebi Üniversitesi, Türkiye
Doç. Dr. Orhan MERAL İzmir Bakırçay Üniversitesi, Türkiye
Prof. Dr. Servet KAVAK İzmir Bakırçay Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı TRACE ELEMENTS AND ELECTROLYTES (Q4)
Dergi ISSN 0946-2104 Dergi Bilgileri (2024)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2024
Kabul Tarihi Yayınlanma Tarihi 01-07-2024
Cilt / Sayı / Sayfa 41 / 3 / 64–71 DOI 10.5414/TE500067
Makale Linki http://dx.doi.org/10.5414/te500067
UAK Araştırma Alanları
Biyofizik
Özet
Objective The aim of this study was to determine the changes in oxidative stress, selenium (Se) and zinc (Zn), and health-related quality of life (HRQoL) following COVID-19 vaccination. Materials and methods 20 healthy male subjects received 2 doses of inactivated COVID-19 vaccines between January and August 2021. Peripheral blood samples were taken immediately before the 1st dose and 3 days after the 2nd dose of the vaccine. The oxidant status (malondialdehyde (MDA) and total oxidant status (TOS)), antioxidant status (superoxide dismutase (SOD) and total antioxidant status (TAS)), Se and Zn, and HRQoL levels of the subjects were evaluated. In addition, oxidative stress index (OSI) was calculated. Results The mean age and body mass index of the subjects were 45.85±6.38 years and 28.53±4.50 kg/m2, respectively. Following COVID-19 vaccinations, TAS levels decreased (p= 0.004); however, SOD levels increased (p= 0.012) significantly. In addition, there were no significant changes in TOS and MDA levels (p> 0.05). Moreover, OSI showed no citation
Anahtar Kelimeler
SARS-CoV-2 | trace element | Se | Zn | quality of life