Efficacy of manual lymph drainage plus exercise on range of motion and flexibility in refractory chronic cutaneous graft-versus-host disease: A case report
 
Yazarlar (4)
Doç. Dr. Kadirhan ÖZDEMİR İzmir Bakırçay Üniversitesi, Türkiye
Prof. Dr. İlke Keser Gazi Üniversitesi, Türkiye
Prof. Dr. Zeynep Arzu Yegin Gazi Üniversitesi, Türkiye
Lale Aydın Kaynar
Gazi Üniversitesi, Türkiye
Makale Türü Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) (SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale)
Dergi Adı CURRENT RESEARCH IN TRANSLATIONAL MEDICINE (Q2)
Dergi ISSN 2452-3186 Dergi Bilgileri (2020)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2020
Cilt / Sayı / Sayfa 68 / 1 / 1–4 DOI 10.1016/j.retram.2019.11.001
Makale Linki https://linkinghub.elsevier.com/retrieve/pii/S2452318619300431
UAK Araştırma Alanları
Fizyoterapi ve Rehabilitasyon
Özet
Graft-versus-host disease (GvHD) is a common complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) with high morbidity and mortality rates. The purpose of this study was to demonstrate the efficacy of Manual Lymph Drainage (MLD) and a home-based exercise programme on range of motion (ROM) and flexibility in a patient diagnosed with chronic cutaneous GvHD. A 29-year-old male who was diagnosed as acute lymphoblastic leukemia underwent allo-HSCT after induction chemotherapy. He developed extended chronic cutaneous skin GvHD. He received systemic immunosuppressive treatment and Psoralen and ultraviolet radiation (PUVA) for 20 sessions. He was then consulted to physiotherapy department for the limitation of multiple ROM due to severe GvHD. The range of motions of shoulder, elbow, hip, knee and ankle joints were evaluated with universal goniometer. The chair sit, reach and back scratch tests were performed. MLD was applied for 2 weeks. Additionally, exercise recommendations were maintained as a home-programme. After the therapy, ROM values were better in wrist extension and hip abduction/adduction and the back scratch test result improved. According to chair sit and reach tests, the results decreased from 25 to 22cm distance after 2 weeks. With MLD treatment with exercise, ROM has been preserved and even improved in this refractory case. In addition, the flexibility test results were found to be increased. The efficacy of MLD and exercise in chronic cutaneous GvHD should be investigated in further studies.
Anahtar Kelimeler
Allogeneic hematopoietic stem cell transplantation | Flexibility | Graft versus host disease | Physiotherapy | Sclerodermatous GVHD